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AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair

Double-strand breaks (DSBs) are the most lethal DNA damages induced by ionising radiation (IR) and their efficient repair is crucial to limit genomic instability. The cellular DSB response after low IR doses is of particular interest but its examination requires the analysis of high cell numbers. He...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lengert, Nicor, Mirsch, Johanna, Weimer, Ratna N., Schumann, Eik, Haub, Peter, Drossel, Barbara, Löbrich, Markus
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251879/
https://ncbi.nlm.nih.gov/pubmed/30470760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35660-5
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