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Increase in double-stranded DNA break-related foci in early-stage thymocytes of aged mice
Cellular and molecular mechanisms involved in aging are notoriously complex. Aging-related immune decline of T lymphocyte function is partly caused by attrition of thymic T cell development, which involves programmed creation and repair of DNA breaks for generating T cell receptors. Aging also leads...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763195/ https://ncbi.nlm.nih.gov/pubmed/19602431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2009.06.009 |
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