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AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair

Double-strand breaks (DSBs) are the most lethal DNA damages induced by ionising radiation (IR) and their efficient repair is crucial to limit genomic instability. The cellular DSB response after low IR doses is of particular interest but its examination requires the analysis of high cell numbers. He...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Lengert, Nicor, Mirsch, Johanna, Weimer, Ratna N., Schumann, Eik, Haub, Peter, Drossel, Barbara, Löbrich, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251879/
https://ncbi.nlm.nih.gov/pubmed/30470760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35660-5
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