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Beyond Repair Foci: DNA Double-Strand Break Repair in Euchromatic and Heterochromatic Compartments Analyzed by Transmission Electron Microscopy

PURPOSE: DNA double-strand breaks (DSBs) generated by ionizing radiation pose a serious threat to the preservation of genetic and epigenetic information. The known importance of local chromatin configuration in DSB repair raises the question of whether breaks in different chromatin environments are...

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Detalhes bibliográficos
Main Authors: Lorat, Yvonne, Schanz, Stefanie, Schuler, Nadine, Wennemuth, Gunther, Rübe, Christian, Rübe, Claudia E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364237/
https://ncbi.nlm.nih.gov/pubmed/22666473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038165
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