Heterochromatic breaks move to the nuclear periphery to continue recombinational repair

Heterochromatin mostly comprises repeated sequences prone to harmful ectopic recombination during double-strand break (DSB) repair. In Drosophila cells, ‘safe’ homologous recombination (HR) repair of heterochromatic breaks relies on a specialized pathway that relocalizes damaged sequences away from...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Cell Biol
Prif Awduron: Ryu, Taehyun, Spatola, Brett, Delabaere, Laetitia, Bowlin, Katherine, Hopp, Hannah, Kunitake, Ryan, Karpen, Gary H., Chiolo, Irene
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628585/
https://ncbi.nlm.nih.gov/pubmed/26502056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3258
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg