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Heterochromatic breaks move to the nuclear periphery to continue recombinational repair
Heterochromatin mostly comprises repeated sequences prone to harmful ectopic recombination during double-strand break (DSB) repair. In Drosophila cells, ‘safe’ homologous recombination (HR) repair of heterochromatic breaks relies on a specialized pathway that relocalizes damaged sequences away from...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628585/ https://ncbi.nlm.nih.gov/pubmed/26502056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3258 |
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