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Nuclear F-actin and myosins drive relocalization of heterochromatic breaks
Heterochromatin mostly comprises repeated DNA sequences prone to ectopic recombination. In Drosophila cells, ‘safe’ homologous recombination repair of heterochromatic double-strand breaks relies on the relocalization of repair sites to the nuclear periphery before strand invasion. Mechanisms respons...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6051730/ https://ncbi.nlm.nih.gov/pubmed/29925946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0242-8 |
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