Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

Double-strand breaks (DSBs) in heterochromatic repetitive DNAs pose significant threats to genome integrity, but information about how such lesions are processed and repaired is sparse. We observe dramatic expansion and dynamic protrusions of the heterochromatin domain in response to ionizing radiat...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Chiolo, Irene, Minoda, Aki, Colmenares, Serafin U., Polyzos, Aris, Costes, Sylvain V., Karpen, Gary H.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417143/
https://ncbi.nlm.nih.gov/pubmed/21353298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.012
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki