Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

Double-strand breaks (DSBs) in heterochromatic repetitive DNAs pose significant threats to genome integrity, but information about how such lesions are processed and repaired is sparse. We observe dramatic expansion and dynamic protrusions of the heterochromatin domain in response to ionizing radiat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Chiolo, Irene, Minoda, Aki, Colmenares, Serafin U., Polyzos, Aris, Costes, Sylvain V., Karpen, Gary H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417143/
https://ncbi.nlm.nih.gov/pubmed/21353298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.02.012
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi