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In cellulo phosphorylation of DNA double-strand break repair protein XRCC4 on Ser260 by DNA-PK

XRCC4 is one of the core factors for DNA double-strand break (DSB) repair through non-homologous end joining (NHEJ). XRCC4 is phosphorylated by DNA-dependent protein kinase (DNA-PK), with Ser260 and Ser320 (Ser318 in the alternatively spliced form) being the major phosphorylation sites in vitro. It...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: Amiri Moghani, Ali Reza, Sharma, Mukesh Kumar, Matsumoto, Yoshihisa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251426/
https://ncbi.nlm.nih.gov/pubmed/30247612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rry072
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