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In cellulo phosphorylation of XRCC4 Ser320 by DNA-PK induced by DNA damage

XRCC4 is a protein associated with DNA Ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end joining. In response to treatment with ionizing radiation or DNA damaging agents, XRCC4 undergoes DNA-PK-dependent phosphorylation. F...

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Dettagli Bibliografici
Pubblicato in:J Radiat Res
Autori principali: Sharma, Mukesh Kumar, Imamichi, Shoji, Fukuchi, Mikoto, Samarth, Ravindra Mahadeo, Tomita, Masanori, Matsumoto, Yoshihisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795952/
https://ncbi.nlm.nih.gov/pubmed/26666690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv086
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