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Ionizing radiation-induced XRCC4 phosphorylation is mediated through ATM in addition to DNA-PK

XRCC4 (X-ray cross-complementation group 4) is a protein associated with DNA ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end-joining. It has been shown that, in response to irradiation or treatment with DNA damaging agen...

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Publicat a:Proc Jpn Acad Ser B Phys Biol Sci
Autors principals: IMAMICHI, Shoji, SHARMA, Mukesh Kumar, KAMDAR, Radhika Pankaj, FUKUCHI, Mikoto, MATSUMOTO, Yoshihisa
Format: Artigo
Idioma:Inglês
Publicat: The Japan Academy 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324928/
https://ncbi.nlm.nih.gov/pubmed/25391321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.90.365
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