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Activation of the apoptotic pathway during prolonged prometaphase blocks daughter cell proliferation
When untransformed human cells spend >1.5 h in prometaphase under standard culture conditions, all daughters arrest in G1 despite normal division of their mothers. We investigate what happens during prolonged prometaphase that leads to daughter cell arrest in the absence of DNA damage. We find th...
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| Veröffentlicht in: | Mol Biol Cell |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249836/ https://ncbi.nlm.nih.gov/pubmed/30133342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-01-0026 |
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