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Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a “tetraploidy checkpoint”
Failure of cells to cleave at the end of mitosis is dangerous to the organism because it immediately produces tetraploidy and centrosome amplification, which is thought to produce genetic imbalances. Using normal human and rat cells, we reexamined the basis for the attractive and increasingly accept...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172377/ https://ncbi.nlm.nih.gov/pubmed/15184397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403014 |
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