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A Rnd3/p190RhoGAP pathway regulates RhoA activity in idiopathic pulmonary fibrosis fibroblasts

Idiopathic pulmonary fibrosis (IPF) is an incurable disease of the lung that is characterized by excessive deposition of extracellular matrix (ECM), resulting in disruption of normal lung function. The signals regulating fibrosis include both transforming growth factor beta (TGF-β) and tissue rigidi...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Monaghan-Benson, Elizabeth, Wittchen, Erika S., Doerschuk, Claire M., Burridge, Keith
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249798/
https://ncbi.nlm.nih.gov/pubmed/29995590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-11-0642
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