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RhoA is down-regulated at cell–cell contacts via p190RhoGAP-B in response to tensional homeostasis

Breast epithelial cells cultured in three-dimensional (3D) collagen gels undergo ductal morphogenesis when the gel is compliant and they can achieve tensional homeostasis. We previously showed that this process requires down-regulation of Rho in compliant collagen gels, but the mechanism remains und...

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Detalhes bibliográficos
Main Authors: Ponik, Suzanne M., Trier, Steven M., Wozniak, Michele A., Eliceiri, Kevin W., Keely, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667722/
https://ncbi.nlm.nih.gov/pubmed/23552690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-05-0386
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