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p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells

Rat pheochromocytoma (PC12) cells have been used to investigate neurite outgrowth. Nerve growth factor (NGF) has been well known to induce neurite outgrowth from PC12 cells. RhoA belongs to Ras-related small GTP-binding proteins, which regulate a variety of cellular processes, including cell morphol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jeon, Chan-Young, Kim, Hee-Jun, Lee, Jae-Yong, Kim, Jaebong, Kim, Sung-Chan, Park, Jae-Bong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877255/
https://ncbi.nlm.nih.gov/pubmed/20200473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.5.035
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