HIV-1 vaccine design through minimizing envelope metastability

Overcoming envelope metastability is crucial to trimer-based HIV-1 vaccine design. Here, we present a coherent vaccine strategy by minimizing metastability. For 10 strains across five clades, we demonstrate that the gp41 ectodomain (gp41(ECTO)) is the main source of envelope metastability by replaci...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Adv
Main Authors: He, Linling, Kumar, Sonu, Allen, Joel D., Huang, Deli, Lin, Xiaohe, Mann, Colin J., Saye-Francisco, Karen L., Copps, Jeffrey, Sarkar, Anita, Blizard, Gabrielle S., Ozorowski, Gabriel, Sok, Devin, Crispin, Max, Ward, Andrew B., Nemazee, David, Burton, Dennis R., Wilson, Ian A., Zhu, Jiang
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2018
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248932/
https://ncbi.nlm.nih.gov/pubmed/30474059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6769
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍