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Divergent TCR-Initiated Calcium Signals Govern Recruitment vs. Activation of Human Alloreactive Effector Memory T cells by Endothelial Cells
Early human allograft rejection can be initiated when circulating human host vs. graft antigen-specific CD8 and CD4 effector memory T cells (T(EM)) directly recognize MHC Class I and II, respectively, expressed on the luminal surface by endothelium lining graft blood vessels. TCR engagement triggers...
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| Publicado no: | J Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6246797/ https://ncbi.nlm.nih.gov/pubmed/30341183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800223 |
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