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Antigen Presentation by Human Microvascular Endothelial Cells Triggers ICAM-1-dependent Transendothelial Protrusion by and Fractalkine-dependent Transendothelial Migration of Effector Memory CD4+ T Cells

TCR engagement on adherent human effector memory (EM) CD4+ T cells by TNF-treated human umbilical vein endothelial cells (HUVEC) under flow induces formation of a transendothelial protrusion (TEP) by the T cell but fails to induce transendothelial migration (TEM). In contrast, TCR engagement of the...

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Detalhes bibliográficos
Main Authors: Manes, Thomas D., Pober, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435282/
https://ncbi.nlm.nih.gov/pubmed/18523306
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