The RhoA GEF, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration

RhoA-mediated cytoskeletal rearrangements in endothelial cells (ECs) play an active role in leukocyte transendothelial cell migration (TEM), a normal physiological process in which leukocytes cross the endothelium to enter the underlying tissue. While much has been learned about RhoA signaling pathw...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lessey-Morillon, Elizabeth C., Osborne, Lukas D., Monaghan-Benson, Elizabeth, Guilluy, Christophe, O’Brien, E. Timothy, Superfine, Richard, Burridge, Keith
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991232/
https://ncbi.nlm.nih.gov/pubmed/24585879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302525
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