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Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway
BACKGROUND: Mechanical forces regulate cell behavior and function during development, differentiation, and tissue morphogenesis. In the vascular system, forces produced by blood flow are critical determinants not only of morphogenesis and function, but also pathological states such as atherosclerosi...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681294/ https://ncbi.nlm.nih.gov/pubmed/23084990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.08.051 |
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