The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

How individual cells respond to mechanical forces is of considerable interest to biologists as force affects many aspects of cell behavior(1). Application of force on integrins triggers cytoskeletal rearrangements and growth of the associated adhesion complex, resulting in increased cellular stiffne...

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Bibliografiske detaljer
Main Authors: Guilluy, Christophe, Swaminathan, Vinay, Garcia-Mata, Rafael, O’Brien, E. Timothy, Superfine, Richard, Burridge, Keith
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107386/
https://ncbi.nlm.nih.gov/pubmed/21572419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2254
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