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Complement-activated human endothelial cells stimulate increased polyfunctionality in alloreactive T cells

Antibody-mediated deposition of complement membrane attack complexes (MACs) on IFN-γ-primed human endothelial cells (ECs) triggers autocrine/paracrine IL-1β-mediated EC activation and IL-15 transpresentation to alloreactive effector memory T cells (T(EM)), changes that enable ECs to increase T cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Transplant
Egile Nagusiak: Xie, Catherine B., Zhou, Jing, Mackay, Sean, Pober, Jordan S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096653/
https://ncbi.nlm.nih.gov/pubmed/33415805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.16485
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