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Complement-activated human endothelial cells stimulate increased polyfunctionality in alloreactive T cells
Antibody-mediated deposition of complement membrane attack complexes (MACs) on IFN-γ-primed human endothelial cells (ECs) triggers autocrine/paracrine IL-1β-mediated EC activation and IL-15 transpresentation to alloreactive effector memory T cells (T(EM)), changes that enable ECs to increase T cell...
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| Published in: | Am J Transplant |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096653/ https://ncbi.nlm.nih.gov/pubmed/33415805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.16485 |
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