m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

N(6)-methyladenosine (m(6)A) mRNA methylation is a gene regulatory mechanism affecting cell differentiation and proliferation in development and cancer. To study the roles of m(6)A mRNA methylation in cell proliferation and tumorigenicity, we investigated human endometrial cancer in which a hotspot...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Liu, Jun, Eckert, Mark A, Harada, Bryan T, Liu, Song-Mei, Lu, Zhike, Yu, Kangkang, Tienda, Samantha M, Chryplewicz, Agnieszka, Zhu, Allen C, Yang, Ying, Huang, Jing-Tao, Chen, Shao-Min, Xu, Zhi-Gao, Leng, Xiao-Hua, Yu, Xue-Chen, Cao, Jie, Zhang, Zezhou, Liu, Jianzhao, Lengyel, Ernst, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245953/
https://ncbi.nlm.nih.gov/pubmed/30154548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0174-4
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