Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer

Endometrial cancer (EC) is the most common gynecological tumor all over the world, and advanced/metastatic EC remains a malignancy with poor survival outcome due to highly resistant to conventional chemotherapeutic treatment. Here, we report that Aurora-A, a serine-threonine kinase, plays a vital ro...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wu, Jun, Cheng, Ziyun, Xu, Xiaofeng, Fu, Jian, Wang, Kaiyue, Liu, Tao, Wu, Chan, Kong, Xiangyi, Yang, Qian, Yan, Guijun, Zhou, Huaijun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540875/
https://ncbi.nlm.nih.gov/pubmed/31192127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00422
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