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Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation
Chemoproteomic methods can report directly on endogenous, active enzyme populations, which can differ greatly from measures of transcripts or protein abundance alone. Detection and quantification of family-wide probe engagement generally requires LC-MS/MS or gel-based detection methods, which suffer...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6815137/ https://ncbi.nlm.nih.gov/pubmed/31591248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912934116 |
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