RADAR: differential analysis of MeRIP-seq data with a random effect model

Epitranscriptome profiling using MeRIP-seq is a powerful technique for in vivo functional studies of reversible RNA modifications. We develop RADAR, a comprehensive analytical tool for detecting differentially methylated loci in MeRIP-seq data. RADAR enables accurate identification of altered methyl...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Zhang, Zijie, Zhan, Qi, Eckert, Mark, Zhu, Allen, Chryplewicz, Agnieszka, De Jesus, Dario F., Ren, Decheng, Kulkarni, Rohit N., Lengyel, Ernst, He, Chuan, Chen, Mengjie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927177/
https://ncbi.nlm.nih.gov/pubmed/31870409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1915-9
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