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Carbenoxolone-mediated cytotoxicity inhibits Vaccinia virus replication in a human keratinocyte cell line

The re-emergence of poxviral zoonotic infections and the threat of bioterrorism emphasise the demand for effective antipoxvirus therapies. Here, we show that carbenoxolone, a pharmacological inhibitor of gap junction function and a compound widely used in cell culture, is capable of hindering the re...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Haga, Ismar R., Simpson, Jennifer L., Hawes, Philippa C., Beard, Philippa M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240113/
https://ncbi.nlm.nih.gov/pubmed/30446704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34732-w
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