A Loss of Function Analysis of Host Factors Influencing Vaccinia virus Replication by RNA Interference

Vaccinia virus (VACV) is a large, cytoplasmic, double-stranded DNA virus that requires complex interactions with host proteins in order to replicate. To explore these interactions a functional high throughput small interfering RNA (siRNA) screen targeting 6719 druggable cellular genes was undertaken...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Beard, Philippa M., Griffiths, Samantha J., Gonzalez, Orland, Haga, Ismar R., Pechenick Jowers, Tali, Reynolds, Danielle K., Wildenhain, Jan, Tekotte, Hille, Auer, Manfred, Tyers, Mike, Ghazal, Peter, Zimmer, Ralf, Haas, Jürgen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047015/
https://ncbi.nlm.nih.gov/pubmed/24901222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098431
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