RAB1A promotes Vaccinia virus replication by facilitating the production of intracellular enveloped virions

Vaccinia virus (VACV) is a large double-stranded DNA virus with a complex cytoplasmic replication cycle that exploits numerous cellular proteins. This work characterises the role of a proviral cellular protein, the small GTPase RAB1A, in VACV replication. Using siRNA, we identified RAB1A as required...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Pechenick Jowers, Tali, Featherstone, Rebecca J., Reynolds, Danielle K., Brown, Helen K., James, John, Prescott, Alan, Haga, Ismar R., Beard, Philippa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292983/
https://ncbi.nlm.nih.gov/pubmed/25462347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.11.007
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