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TRAF2 Facilitates Vaccinia Virus Replication by Promoting Rapid Virus Entry

Tumor necrosis factor receptor (TNFR)-associated factor 2 (TRAF2) is a pivotal intracellular mediator of signaling pathways downstream of TNFR1 and -2 with known pro- and antiviral effects. We investigated its role in the replication of the prototype poxvirus vaccinia virus (VACV). Loss of TRAF2 exp...

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Autors principals: Haga, Ismar R., Pechenick Jowers, Tali, Griffiths, Samantha J., Haas, Juergen, Beard, Philippa M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993545/
https://ncbi.nlm.nih.gov/pubmed/24429366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03013-13
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