Antiviral activity of the mineralocorticoid receptor NR3C2 against Herpes simplex virus Type 1 (HSV-1) infection

Analysis of a genome-scale RNA interference screen of host factors affecting herpes simplex virus type 1 (HSV-1) revealed that the mineralocorticoid receptor (MR) inhibits HSV-1 replication. As a ligand-activated transcription factor the MR regulates sodium transport and blood pressure in the kidney...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Haas, Jürgen G., Weber, Julia, Gonzalez, Orland, Zimmer, Ralf, Griffiths, Samantha J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203759/
https://ncbi.nlm.nih.gov/pubmed/30367157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34241-w
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