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Inhibition of vaccinia virus replication by nitazoxanide
Nitazoxanide (NTZ) is an FDA-approved anti-protozoal drug that inhibits several bacteria and viruses as well. However, its effect on poxviruses is unknown. Therefore, we investigated the impact of NTZ on vaccinia virus (VACV). We found that NTZ inhibits VACV production with an EC(50) of ~2μM, a pote...
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| Publicado no: | Virology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929478/ https://ncbi.nlm.nih.gov/pubmed/29625403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.023 |
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