Hsp90 Inhibition Decreases Mitochondrial Protein Turnover

BACKGROUND: Cells treated with hsp90 inhibitors exhibit pleiotropic changes, including an expansion of the mitochondrial compartment, accompanied by mitochondrial fragmentation and condensed mitochondrial morphology, with ultimate compromise of mitochondrial integrity and apoptosis. FINDINGS: We ide...

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Detaylı Bibliyografya
Asıl Yazarlar: Margineantu, Daciana H., Emerson, Christine B., Diaz, Dolores, Hockenbery, David M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031825/
https://ncbi.nlm.nih.gov/pubmed/17957250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001066
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