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Inhibition of vaccinia virus replication by nitazoxanide

Nitazoxanide (NTZ) is an FDA-approved anti-protozoal drug that inhibits several bacteria and viruses as well. However, its effect on poxviruses is unknown. Therefore, we investigated the impact of NTZ on vaccinia virus (VACV). We found that NTZ inhibits VACV production with an EC(50) of ~2μM, a pote...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Virology
Päätekijät: Hickson, Sarah E., Margineantu, Daciana, Hockenbery, David M., Simon, Julian A., Geballe, Adam P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929478/
https://ncbi.nlm.nih.gov/pubmed/29625403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.023
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