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A NEW MOUSE MODEL TO UNRAVEL THE MECHANISM OF SIRT1 ACTIVATION
SIRT1 is an NAD+-dependent deacetylase and one of the seven-member family of sirtuins that play a key role in the regulation of metabolism, DNA repair, inflammation, chromatin structure, and aging in mammals. Activation of SIRT1 improves mitochondrial function, treats hyperglycemia and fatty liver i...
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| 出版年: | Innov Aging |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6239378/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy031.3277 |
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