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Synthesis and Assay of SIRT1-Activating Compounds
The NAD(+)-dependent deacetylase SIRT1 plays key roles in numerous cellular processes including DNA repair, gene transcription, cell differentiation, and metabolism. Over-expression of SIRT1 protects against a number of age-related diseases including diabetes, cancer, and Alzheimer's disease. M...
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| Published in: | Methods Enzymol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127272/ https://ncbi.nlm.nih.gov/pubmed/27423864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.01.012 |
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