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Sirtuin 6 (SIRT6) Activity Assays

SIRT6 has been shown to possess weak deacetylation, mono-ADP-ribosyltransferase activity, and deacylation activity in vitro. SIRT6 selectively deacetylates H3K9Ac and H3K56Ac. Several SIRT6 assays have been developed including HPLC assays, fluorogenic assays, FRET, magnetic beads, in silico, and bio...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Rahnasto-Rilla, Minna, Lahtela-Kakkonen, Maija, Moaddel, Ruin
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004593/
https://ncbi.nlm.nih.gov/pubmed/27246220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3667-0_17
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