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Sirtuin 6 (SIRT6) Activity Assays

SIRT6 has been shown to possess weak deacetylation, mono-ADP-ribosyltransferase activity, and deacylation activity in vitro. SIRT6 selectively deacetylates H3K9Ac and H3K56Ac. Several SIRT6 assays have been developed including HPLC assays, fluorogenic assays, FRET, magnetic beads, in silico, and bio...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Rahnasto-Rilla, Minna, Lahtela-Kakkonen, Maija, Moaddel, Ruin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004593/
https://ncbi.nlm.nih.gov/pubmed/27246220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3667-0_17
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