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An improved fluorogenic assay for SIRT1, SIRT2, and SIRT3

Sirtuins are NAD-dependent lysine deacylases that play critical roles in cellular regulation and are implicated in human diseases. Modulators of sirtuins are needed as tools for investigating their biological functions and possible therapeutic applications. However, the discovery of sirtuin modulato...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Chiang, Ying-Ling, Lin, Hening
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860349/
https://ncbi.nlm.nih.gov/pubmed/26796034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02609a
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