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Fluorogenic Assays for the Defatty-Acylase Activity of Sirtuins
Sirtuins are type III histone deacetylases (HDAC) that uses nicotinamide adenine dinucleotide as co-substrate. Dysfunction of sirtuins is implicated in wide varieties of human diseases. As such, there has been increased interest in development of small molecule to modulate sirtuin activities. Beside...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6893880/ https://ncbi.nlm.nih.gov/pubmed/31152400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9532-5_10 |
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