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Updates on the Epigenetic Roles of Sirtuins

Sirtuins are a class of enzyme with NAD(+)-dependent protein lysine deacylase activities. They were initially discovered to regulate transcription and life span via histone deacetylase activities. Later studies expanded their activities to other proteins and acyl lysine modifications. Through deacyl...

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Bibliografiske detaljer
Udgivet i:Curr Opin Chem Biol
Main Authors: Kosciuk, Tatsiana, Wang, Miao, Hong, Jun Young, Lin, Hening
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698398/
https://ncbi.nlm.nih.gov/pubmed/30875552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2019.01.023
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