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Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

Telomeres play crucial roles during tumorigenesis, inducing cellular senescence upon telomere shortening and extensive chromosome instability during telomere crisis. However, it has not been investigated if and how cellular transformation and oncogenic stress alter telomeric chromatin composition an...

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Bibliografske podrobnosti
izdano v:Life Sci Alliance
Main Authors: Majerska, Jana, Feretzaki, Marianna, Glousker, Galina, Lingner, Joachim
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238619/
https://ncbi.nlm.nih.gov/pubmed/30456372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800121
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