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Human shelterin protein POT1 prevents severe telomere instability induced by homology‐directed DNA repair
The evolutionarily conserved POT1 protein binds single‐stranded G‐rich telomeric DNA and has been implicated in contributing to telomeric DNA maintenance and the suppression of DNA damage checkpoint signaling. Here, we explore human POT1 function through genetics and proteomics, discovering that a c...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705456/ https://ncbi.nlm.nih.gov/pubmed/33073402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104500 |
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