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Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

Telomeres play crucial roles during tumorigenesis, inducing cellular senescence upon telomere shortening and extensive chromosome instability during telomere crisis. However, it has not been investigated if and how cellular transformation and oncogenic stress alter telomeric chromatin composition an...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Majerska, Jana, Feretzaki, Marianna, Glousker, Galina, Lingner, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238619/
https://ncbi.nlm.nih.gov/pubmed/30456372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800121
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