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Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

Telomeres play crucial roles during tumorigenesis, inducing cellular senescence upon telomere shortening and extensive chromosome instability during telomere crisis. However, it has not been investigated if and how cellular transformation and oncogenic stress alter telomeric chromatin composition an...

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Библиографические подробности
Опубликовано в: :Life Sci Alliance
Главные авторы: Majerska, Jana, Feretzaki, Marianna, Glousker, Galina, Lingner, Joachim
Формат: Artigo
Язык:Inglês
Опубликовано: Life Science Alliance LLC 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238619/
https://ncbi.nlm.nih.gov/pubmed/30456372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800121
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