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The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening
Telomere maintenance by the conventional DNA replication machinery and telomerase is assisted by specialized DNA helicases, nucleases and telomere binding proteins. Here, we identify the THO components at telomeres and define critical roles of this complex in telomere stability. Deletion of the THO-...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
European Molecular Biology Organization
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817467/ https://ncbi.nlm.nih.gov/pubmed/24084588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.217 |
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