Chargement en cours...

TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

The long noncoding telomeric repeat containing RNA (TERRA) is expressed at chromosome ends. TERRA upregulation upon experimental manipulation or in ICF (immunodeficiency, centromeric instability, facial anomalies) patients correlates with short telomeres. To study the mechanism of telomere length co...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pfeiffer, Verena, Lingner, Joachim
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375253/
https://ncbi.nlm.nih.gov/pubmed/22719262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002747
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!