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Notch signaling promotes a HIF2α-driven hypoxic response in multiple tumor cell types
Hyperactivation of Notch signaling and the cellular hypoxic response are frequently observed in cancers, with increasing reports of connections to tumor initiation and progression. The two signaling mechanisms are known to intersect, but while it is well established that hypoxia regulates Notch sign...
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| Publicat a: | Oncogene |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237764/ https://ncbi.nlm.nih.gov/pubmed/29993038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0400-3 |
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