PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner

Activation of Notch signaling requires intracellular routing of the receptor, but the mechanisms controlling the distinct steps in the routing process is poorly understood. We identify PKCζ as a key regulator of Notch receptor intracellular routing. When PKCζ was inhibited in the developing chick ce...

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Autori principali: Sjöqvist, Marika, Antfolk, Daniel, Ferraris, Saima, Rraklli, Vilma, Haga, Cecilia, Antila, Christian, Mutvei, Anders, Imanishi, Susumu Y, Holmberg, Johan, Jin, Shaobo, Eriksson, John E, Lendahl, Urban, Sahlgren, Cecilia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975507/
https://ncbi.nlm.nih.gov/pubmed/24662486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.34
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