Antioxidant metabolism regulates CD8(+) T memory stem cell formation and antitumor immunity

Adoptive T cell transfer (ACT) immunotherapy benefits from early differentiated stem cell memory T (Tscm) cells capable of persisting in the long term and generating potent antitumor effectors. Due to their paucity ex vivo, Tscm cells can be derived from naive precursors, but the molecular signals a...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Pilipow, Karolina, Scamardella, Eloise, Puccio, Simone, Gautam, Sanjivan, De Paoli, Federica, Mazza, Emilia M.C., De Simone, Gabriele, Polletti, Sara, Buccilli, Marta, Zanon, Veronica, Di Lucia, Pietro, Iannacone, Matteo, Gattinoni, Luca, Lugli, Enrico
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237218/
https://ncbi.nlm.nih.gov/pubmed/30232291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122299
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